Assistance for a Chaperone

Assistance for a chaperone: Chlamydomonas HEP2 activates plastidic HSP70B for cochaperone binding.

Previous efforts aimed at the biochemical characterization of chloroplast HSP70B were hampered by the observation that recombinant HSP70B was inactive, i.e. incompetent of interacting with its nucleotide exchange factor CGE1. In addition, because heterologously expressed mitochondrial Hsp70 was inactive unless coexpressed with the escort protein Hep1, we wondered whether homologs of Hep1 existe...

Ribosomal crystallography: peptide bond formation, chaperone assistance and antibiotics activity.

The peptidyl transferase center (PTC) is located in a protein free environment, thus confirming that the ribosome is a ribozyme. This arched void has dimensions suitable for accommodating the 3' ends of the A-and the P-site tRNAs, and is situated within a universal sizable symmetry-related region that connects all ribosomal functional centers involved in amino-acid polymerization. The linkage b...

Ribosomal Crystallography: Peptide Bond Formation, Chaperone Assistance, and Antibiotics Inactivation

The peptidyl transferase center (PTC) is an arched void has dimensions suitable for accommodating the 3′ ends of the A-and the P-site tRNAs. It is situated within a universal sizable symmetrical region that connects all ribosomal functional centers involved in aminoacid polymerization. The linkage between the elaborate PTC architecture and the A-site tRNA position revealed that the Ato P-site p...

Surgical competence in general surgery assistance: a brief report

Evaluation of Nutritional Assistance Education Models: A Systematic Review

Background: The establishment of good eating practices will impact lifelong nutritional habits and overall health that begins in infancy. This study was conducted to evaluate effective educational models to increase parents' knowledge and awareness in the field of nutritional assistance to toddlers through published articles in the time frame of 2010-2021. Methods: PubMed, Sciencedirect, Web o...